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Will New TB Diagnostics Make a Difference? Roundtable Discussion on the Role of Clinical/Empiric Diagnosis

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Total Posts: 16

Joined 2014-04-02

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This interactive session utilizes the opinions of TB researchers at Hopkins as they respond to data that show how novel tools impact global estimates.  As stand-alone developments, even the most promising tools of TB control, such as GeneXpert, are not magic bullets that can reverse the epidemic.

     
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Total Posts: 24

Joined 2014-05-05

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How GeneXpert still recommended ? is it still worth in practice ?

     
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Total Posts: 21

Joined 2014-05-04

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Genexpert will help to detect TB cases but is the basic infrastructure available - manpower, drugs available to treat and off course the adherence to treatment. So these newer diagnostics need to be sensitive, cheap readily available and needs to be coupled with availability of infrastructure to treat and follow-up these patients or else we may be heading for more and more extensive drug resistance cases.

     
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Total Posts: 14

Joined 2014-05-07

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New diagnostic tests are needed for tuberculosis and will make a difference in TB control.Gene expert is of course not the ideal test we are looking for.

Take home messages: There could be some expected and some unanticipated effects of a new diagnostic test as has been described in the lecture.The performance of a test may be very different in clinical trials and under programmatic settings. When we strengthen the diagnostics it is imperative to make provisions for treatment too.

Considering the costs involved could we restrict the use of expert for specific indications e.g. defaulters, relapse,HIV cases.

     
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Total Posts: 10

Joined 2014-05-06

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That was a wonderful and lively interactive discussion on an important topic.

My country has a high burden of TB and I feel here patient delay is the most imp cause of undetected TB and spread.If patient awareness and education makes them approach the health care system directly without delay and in Health Care system a good and fast diagnostic test like X-pert is available thereby avoiding diagnostic and treatment delay a substantial difference in outcome and incidence of new cases will be done.

We at present relay on clinical diagnostics,X-ray and Sputum smear but the patient should reach us instead of going to the nearest unqualified health consultant .So even though new rapid and cheap test eg like the malaria antigen stat test is invented for TB a educational activity to increase awareness and availability of diagnostics within 3 km diameter of patients residence(easy accesibility) will help decreasing the incidence.X-pert should be cheaper and more widely available.lost to follow up is high if diagnostics take a long time to give a report.So new rapid ,reliable,easily available and cheaper diagnostics will surely make a difference.and simultaneously all patient should be completely cured and compliant.
                    Dr Anita basavaraj